Cannabinodiol (CBND): Specs, Where It Fits & Evidence

Cannabinoid · Phytocannabinoid

Cannabinodiol (CBND) is a phytocannabinoid made by the cannabis plant, in the CBN-type group. A fully aromatic relative of CBD.

Where it fits

What the research shows

Direct human research on Cannabinodiol (CBND) is minimal; it is characterised mainly by its chemistry and its place in the cannabinoid family rather than by clinical studies. We flag that plainly rather than overstate it.

FAQ

Is CBND intoxicating? No. Cannabinodiol (CBND) is non-intoxicating.

Where does CBND come from? From CBD (aromatization).

How does CBND relate structurally to CBN? CBND (C21H26O2) is the open-chain biphenyl isomer of cannabinol (CBN), formed by aromatization of CBD without closing the central pyran ring.

Aromatization of CBD, Biphenyl Structure, and Relationship to CBN

Cannabinodiol (CBND, C21H26O2) is a fully aromatic phytocannabinoid formed by photochemical or oxidative dehydrogenation of cannabidiol (CBD), paralleling how THC oxidizes into cannabinol (CBN) (Lousberg et al., 1977, PubMed PMID 320427). Whereas CBD contains a cyclohexene terpene ring attached to a resorcinol ring, aromatization converts that terpene ring into a second benzene ring, giving CBND an open-chain biphenyl structure that is the structural isomer of tricyclic CBN (Hanuš et al., 2016, PubMed PMID 28861498).

Part of the NOIDS cannabinoids index. Educational reference, not medical advice.