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A 2017 US National Academies review found substantial evidence that cannabis is effective for chronic pain in adults, though it is not a cure and not right for everyone. Of all the conditions cannabis is used for, chronic pain has the strongest research base.
What the research says
The National Academies (NASEM) 2017 report found substantial evidence for cannabis in adult chronic pain, especially neuropathic (nerve) pain. Effects are typically moderate, reducing pain rather than eliminating it, and results vary between people. It is often considered when conventional options have limits or side effects.
Which compounds are studied
Both THC and balanced THC:CBD preparations have been studied. The prescription mouth spray nabiximols (Sativex), a roughly 1:1 THC:CBD extract, is approved in several countries for some pain and spasticity indications. CBD alone has weaker evidence for pain.
How people use it
For non-smoking use, oral forms (oils, capsules, edibles) and sublingual sprays are common. Oral onset is slow (30 to 120 minutes) and effects last longer, which suits steady pain but makes careful dosing important. The potency calculator and dosage guides help avoid overshooting.
At a glance
What to be careful about
THC can cause dizziness, impairment and, in some, anxiety; tolerance can build; and cannabis interacts with some medications. It is not a first-line treatment for everyone and should be discussed with a clinician, especially alongside other pain medicines.
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