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PL Cannabinoid index · Non-intoxicating
CBC (cannabichromene) is a non-intoxicating minor cannabinoid, one of the “big six” the plant produces. Like the others it starts as an acid (CBCA) that converts to CBC with heat. Research is almost entirely preclinical: there are no approved CBC medicines and no significant human trials.
Decarboxylation & infusion
CBC is a trace component of most flower; see the decarboxylation temperature chart.
Reviewed 2026-09-04. Not legal or medical advice.
What the published literature examined
CBC has been studied mainly in vitro and in rodents. Work has looked at anti-inflammatory and analgesic signals in animal models and at how CBC interacts with receptors such as TRPA1, as well as the idea that it contributes to combined “entourage” effects alongside other cannabinoids. This is early-stage research, not clinical evidence.
What is established, and what is not
Established: that CBC is a genuine, non-intoxicating phytocannabinoid present in small amounts and active at certain receptors in laboratory work. Not established: any human clinical effect. There are no registered human trials of note and no approved use. Wellness claims for CBC run well ahead of the evidence. This page describes the compound and summarises research; it is not medical advice.
Sources
- Izzo AA, et al. Non-psychotropic plant cannabinoids: new therapeutic opportunities from an ancient herb. Trends Pharmacol Sci. 2009;30:515-527. PubMed
- Udoh M, et al. Cannabichromene and related pharmacology. Reviews of minor cannabinoids. PubMed
- Registered human studies for cannabichromene. ClinicalTrials.gov
- World Anti-Doping Agency. Prohibited List (cannabinoids, CBD excepted). wada-ama.org
Frequently asked questions
Does CBC get you high?
No. CBC is non-intoxicating and does not produce a THC-like high.
Is there human research on CBC?
Very little. CBC research is almost entirely cell and animal studies; there are no significant registered human trials and no approved CBC medicine.
Where does CBC come from?
From CBCA, one of the acids the plant makes from the precursor CBGA. Heat converts CBCA to CBC. It is usually only a trace component of flower.
Part of the cannabinoid index.
Educational information about a compound. Not medical advice or guidance on use.
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