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PL Cannabinoid · Pharmaceutical (synthetic analog)
Nabilone is a synthetic analog of THC — a designed molecule, not identical to THC — that is FDA-approved as Cesamet for chemotherapy-induced nausea and vomiting that has failed to respond to standard anti-nausea drugs. Being synthetic and orally stable makes its dosing predictable.
A designed THC analog
Not the same molecule as THC
Unlike dronabinol (which is THC), nabilone is a structurally distinct synthetic that acts at the same CB1 receptor. It is reserved for chemotherapy nausea unresponsive to conventional treatment, and is also used off-label in some pain and spasticity settings.
FAQ
Is nabilone the same as THC? No. It is a synthetic analog of THC — a different molecule that acts on the same CB1 receptor — approved as the medicine Cesamet.
What is nabilone prescribed for? Chemotherapy-induced nausea and vomiting that has not responded to standard anti-nausea medication.
Sources
- Nabilone (Cesamet) FDA prescribing information, DailyMed. dailymed.nlm.nih.gov
Part of the NOIDS cannabinoids index. Educational reference, not medical advice.
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